Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study by the Japanese CHIRP NITE

Data source

Reference
Reference Type:
secondary source
Title:
Unnamed
Year:
1994
Report Date:
1994

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
Principles of method if other than guideline:
MITI according to Japanese standard protocol
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent

Study design

Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, domestic, non-adapted
Details on inoculum:
30 mg/l activated sludge was used.
Duration of test (contact time):
28 d
Initial test substance concentration
Initial conc.:
100 mg/L
Based on:
test mat.
Reference substance
Reference substance:
not specified

Results and discussion

% Degradationopen allclose all
Parameter:
% degradation (test mat. analysis)
Value:
1
Sampling time:
28 d
Parameter:
% degradation (inorg. C analysis)
Value:
0
Sampling time:
28 d
Parameter:
% degradation (O2 consumption)
Value:
1
Sampling time:
28 d
Details on results:
Not readily biodegradable

BOD5 / COD results

Results with reference substance:
assume acceptable

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Remarks:
according to Japanese NITE requirements
Interpretation of results:
under test conditions no biodegradation observed
Conclusions:
3-Cyanopyridine was not readily biodegradable in a ready biodegradability test using the MITI (OECD 301C) protocol.