Registration Dossier

Administrative data

Description of key information

3-Cyanopyridine is not irritating to skin, but causes severe damage to eyes.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

3-Cyanopyridine was found to be non-irritating to the skin of rabbits after 3 or 60 minutes, and 4 hours. However, application of 0.1 ml into the eyes of rabbits resulted in severe damage which persisted throughout 21 days. There is no data available for respiratory irritation.

Effects on eye irritation: highly irritating

Justification for classification or non-classification

3 -Cyanopyridine is not classified for irritation to skin or the respiratory tract. It is classified for eye irritation as a Category 1 substance, causing severe damage to the eye, according to Regulation (EC) No. 1272/2008.