Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data was not generated using guideline protocols or organisms, but the study is scientifically valid from a reputable laboratory

Data source

Reference
Reference Type:
publication
Title:
Structure-activity relationships of selected pyridines. III Log Kow analysis
Author:
Schultz T et.al
Year:
1987
Bibliographic source:
Ecotoxicol Environ Safety 13:76

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Survival of organism in assays after exposure to test material.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent

Test organisms

Test organisms (species):
other: Tetrahymena pyriformis

Results and discussion

Effect concentrations
Duration:
2.5 d
Dose descriptor:
EC50
Effect conc.:
581.6 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: growth

Applicant's summary and conclusion

Validity criteria fulfilled:
not applicable
Remarks:
not a guideline study
Conclusions:
3-Cyanopyridine has an EC50 for Tetrahymena pyriformis of 581.6 mg/L.