Registration Dossier
Registration Dossier
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EC number: 423-630-1 | CAS number: 62435-71-6
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 14 days
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Justification for type of information:
- Performed to guidelines to national quality assurance standards
However, report lacking in method details and only summary of results included. This does not impact on the conclusions of the study. - Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
- GLP compliance:
- yes
- Remarks:
- Chinese certified
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Duration of test (contact time):
- ca. 14 d
- Based on:
- not specified
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- Test mixture contains an inorganic medium, activated sludge as a mixed inoculum and the test compound as the sole source of carbon and energy other than sludge.
- Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (test mat. analysis)
- Value:
- ca. 100
- Sampling time:
- 14 d
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The test material attained 100% degradation in less than 14 days through DOC removal methods
Althought the test report lacked interim measurements, it can be safely assumed that 60% degradation was attained in under a 10 day period
Reference
The inherent biodegradability in the static test of reference substance sodium benzoate after 7 days was 88.8, and the inherent biodegradability after 14 days was 95.8%.
A toxicity control showednottoxic effect.
The max. % degradtion of test substance THFEE was 100% at the 14th day. The inherent biodegradability after 15 days was 100%
During the test the pH was between 6.5 and 7.5 and the dissolved oxygen conc. was between 6.8mg/L and 8.0 mg/L.
Description of key information
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
The test material attained 100% degradation in less than 14 days through DOC removal methods Although the test report lacked interim measurements, it can be safely assumed that 60% degradation was attained in under a 10 day period
It is noted that glycols fail to biodegrade in closed-bottle tests
Ref: Žgajnar Gotvajn A, Zagorc-Končan J. BIODEGRADABILITY ASSESSMENT OF DIETHYLENE GLYCOL AND PHENOL Arh Hig Rada Toksikol 2003;54:189-19
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