Registration Dossier

Administrative data

Key value for chemical safety assessment

Additional information

All in vitro genotoxicity studies conducted with DIBK showed clearly negative results. DIBK did not induce gene mutation in bacteria nor in mammalian cells and DIBK did also not induce chromosome aberrations in mammalian cells.

No in vivo genotoxicity studies are available with DIBK.


Short description of key information:
GLP-studies according to or equivalent to OECD guidelines 471, 473 and 476 are available for diisibutylketone.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

All in vitro genotoxicity studies conducted with DIBK showed clearly negative results. Hence, no classification for genotoxicity is applicable for DIBK.