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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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CAS# 756-13-8 is very volatile (VP 40 kPa at 25°C). During routine use, there is no anticipated release to water or wastewater in the EU. It is not expected to partition from air to aquatic systems. The modest amount of CAS# 756-13-8 which would partition from air to water would hydrolyze with a half-life of ca. 2.5 minutes. We have proposed waiving of tests of bioconcentration for CAS# 756-13-8. The expected phototransformation products are very soluble (if not miscible) in water. PFPA has a measured BCF of <4.8 in carp and is not considered bioaccumulative. TFA as a smaller molecule (CF3CO2H v. CF3CF2CO2H) is expected to be less bioaccumulative in fish than PFPA. At concentrations at or below the no effect level of 1 mg/L, literature BCF values in terrestrial plants ranged from 5.4 to 27(1). It should be noted that growth dilution and root excretion will result in the reduction of plant TFA concentrations while leaf fall from deciduous plants is an ultimate removal mechanism. It is believed that the TFA is transported into the shoots from the roots via either flow due to transpiration or xylem flow and left behind when the water exited the plant. When removed to clean media, clearance of TFA from plants was observed. Therefore TFA is not bioaccumulative in terrestrial plants.



1. Boutonnet (Ed)., 1999. Environmental Risk Assessment of Trifluoroacetic Acid. Human and Ecological Risk Assessment: Vol. 5, No. 1, pp. 59-124.