Registration Dossier
Registration Dossier
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EC number: 436-710-6 | CAS number: 756-13-8
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
- Report date:
- 2002
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: other guideline: EC Directive 96/54/EC, Part B.1 tris OECD 423, 1996
- GLP compliance:
- yes
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- -
- EC Number:
- 436-710-6
- EC Name:
- -
- Cas Number:
- 756-13-8
- Molecular formula:
- C6F12O
- IUPAC Name:
- 1,1,1,2,2,4,5,5,5-nonafluoro-4-(trifluoromethyl)pentan-3-one
Constituent 1
Test animals
- Species:
- other: Rat, Wistar Crl:(WI)BR
Administration / exposure
- Vehicle:
- other: None
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Mortality:
- Male: 2000 mg/kg bw; Number of animals: 3; Number of deaths: 0
Female: 2000 mg/kg bw; Number of animals: 3; Number of deaths: 0 - Clinical signs:
- other: Signs of toxicity related to dose levels: Lethargy, hunched posture and/or piloerection were notedamong all animals between days 1 and 7.
- Gross pathology:
- Effects on organs:
No abnormalities were found at macroscopic post mortem examination of the animals.
Applicant's summary and conclusion
- Interpretation of results:
- other: not classified
- Remarks:
- Criteria used for interpretation of results: EU
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