Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-846-5 | CAS number: 88-63-1
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
The Soil Adsorption Coefficient i.e Koc value of 2,4-Diaminobenzenesulfonic acid was estimated using EPI suite KOCWIN Program (v2.00) program as Koc 10 L/kg(log Koc=1) by means of MCI method at 25 deg.C. This Koc value indicates that the substance 2,4-Diaminobenzenesulfonic acid has a Negligible sorption to soil and sediment and therefore have rapid migration potential to groundwater.
Key value for chemical safety assessment
- Koc at 20 °C:
- 10
Additional information
Experimental and Predicted data of adsorption endpoint for the target chemical 2,4-Diaminobenzenesulfonic acid (Cas no. 88-63-1) and its read across chemical were reviewed to summarize as follows:
From predicted model EPI suite 2016 and chemspider predicted database indicate that the soil adsorption coefficient (Koc) value of chemical 2,4-Diaminobenzenesulfonic acid is estimated to be 10 L/kg (log KOC = 1) by means of MCI method at 25 deg.C, indicating that it is has a Negligible sorption to soil and sediment and therefore have rapid migration potential to groundwater.
For the read across substance, Sulfanilic acid (Cas no. 121-57-3), experimental study from HSDB authorative database also indicate that the adsorption coefficient (Koc) of substance Sulfanilic acid was found to be 10 using a structure estimation method based on molecular connectivity indices. This Koc value suggests that Sulfanilic acid is expected to have very high mobility in soil.
Both the results reported above are further supported by read across 2-aminobenzene-1, 4-disulphonic acid (Cas no. 98-44-2) for which information in Scifinder database indicates the Koc value of 2-aminobenzene-1, 4-disulphonic acid is estimated to be 10 at pH: 1-10 and Temp: 25 °C.
Thus based on the above all studies it is concluded that the test substance 2,4-Diaminobenzenesulfonic acid (Cas no. 88-63-1) has a negligible sorption to soil and sediment i.e have rapid migration to ground water.
[LogKoc: 1.0]
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
