Registration Dossier

Administrative data

Endpoint:
bioaccumulation: aquatic / sediment
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
review article or handbook
Title:
ChemSpider ID: 59990
Author:
Chemspider - ACD/PhysChem Suite
Year:
2012
Bibliographic source:
ChemSpider- Free chemical Database, Royal Society of Chemistry.

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: refer below principle
Principles of method if other than guideline:
Bioaccumulation test was conducted for estimating the bioconcentration factor (BCF) of 2,4-Diaminobenzenesulfonic acid.
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: solid
Details on test material:
- Name of test material (as cited in study report): 2,4-Diaminobenzenesulfonic acid- Molecular formula (if other than submission substance): C6H8N2O3S- Molecular weight (if other than submission substance): 188.206 g/mol- Smiles notation (if other than submission substance): O=S(=O)(O)c1c(N)cc(N)cc1- InChl (if other than submission substance): 1S/C6H8N2O3S/c7-4-1-2-6(5(8)3-4)12(9,10)11/h1-3H,7-8H2,(H,9,10,11)- Structural formula attached as image file (if other than submission substance): No data available- Substance type: Organic- Physical state: Solid- Analytical purity: No data available- Impurities (identity and concentrations): No data available- Composition of test material, percentage of components: No data available- Isomers composition: No data available- Purity test date: No data available- Lot/batch No.: No data available- Expiration date of the lot/batch: No data available- Radiochemical purity (if radiolabelling): No data available- Specific activity (if radiolabelling): No data available- Locations of the label (if radiolabelling): No data available- Expiration date of radiochemical substance (if radiolabelling): No data available- Stability under test conditions: No data available- Storage condition of test material: No data available- Other: No data available
Specific details on test material used for the study:
Details on properties of test surrogate or analogue material (migrated information):No data available
Radiolabelling:
not specified

Sampling and analysis

Details on sampling:
No data available

Test solutions

Vehicle:
not specified
Details on preparation of test solutions, spiked fish food or sediment:
No data available

Test organisms

Test organisms (species):
no data
Details on test organisms:
No data available

Study design

Test type:
not specified
Water / sediment media type:
not specified

Test conditions

Hardness:
No data available
Test temperature:
No data available
pH:
At pH 5.5 and 7.4
Dissolved oxygen:
No data available
TOC:
No data available
Salinity:
No data available
Details on test conditions:
No data available
Nominal and measured concentrations:
No data available
Reference substance (positive control):
not specified
Details on estimation of bioconcentration:
No data available

Results and discussion

Bioaccumulation factor
Type:
BCF
Value:
1 dimensionless
Basis:
not specified
Calculation basis:
other: estimated
Remarks on result:
other: The BCF value was obatined at pH 5.5 and 7.4, respectively.
Details on kinetic parameters:
No data available
Metabolites:
No data available
Results with reference substance (positive control):
No data available
Details on results:
No data available
Reported statistics:
No data available

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
The bioconcentration factor of test substance was found to be 1.00 at pH 5.5 and 7.4 respectively.
Executive summary:

Bioaccumulation test was conducted for estimating the bioconcentration factor (BCF) of test substance2,4-Diaminobenzenesulfonic acid.

 

The bioconcentration factor of 2,4-Diaminobenzenesulfonic acidwas found to be 1.00 at pH 5.5 and 7.4 respectively.