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EC number: 931-433-1 | CAS number: -
The key acute oral toxicity study gave an LD50 (oral) >2000 mg/kg bw (OECD 423, acute toxic class method) in rats (Wolf, 2005). There were no clinical signs or necropsy findings. The key acute dermal toxicity study gave an LD50 (dermal) >2000 mg/kg bw (OECD 402, limit test) in rats (Bernat, 2005). There were no clinical signs, signs of local irritation or necrospy findings.
Acute oral toxicity:
Three acute oral toxicity studies are available for Crude Tall Oil. In all cases, the observed LD50 was greater than 2000 mg/kg bw. The key study was selected as the most recent study which was conducted in accordance with OECD Test Guideline 423 and in compliance with GLP (Wolf, 2005).
Acute dermal toxicity:
Only one acute dermal toxicity study is available for Crude Tall Oil. The test was carried out in accordance with OECD Test Guideline 402 (limit test) and in compliance with GLP (Bernat, 2005). The observed LD50 was greater than 2000 mg/kg bw.
The available data for acute oral and dermal toxicity in the rat indicate that Crude Tall Oil is not classified for acute toxicity according to the criteria of EU Directive 67/548/EEC or Regulation 1272/2008.
There are no data available for the inhalation route.
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