Registration Dossier
Registration Dossier
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EC number: 206-996-5 | CAS number: 420-46-2
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: screening tests
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Use of validated model
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- publication
- Title:
- Multimedia environmental models: the fugacity approach
- Author:
- Mackay, D.
- Year:
- 2 001
- Bibliographic source:
- Multimedia environmental models: the fugacity approach. 2nd ed. Lewis, Boca Raton, FL, USA
Materials and methods
- Principles of method if other than guideline:
- Biowin1:(linear Model Prediction, Biowin2 (Nonlinear model prediction), Biowin3 (Ultimate Biodegredation Timeframe), Biowin 4 (Promary Biodegredation Timeframe), Biowin5 (MITI Linear Model Prediction) and Biowin6 (MITI Non-linear Model Prediction).
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1,1,1-trifluoroethane
- EC Number:
- 206-996-5
- EC Name:
- 1,1,1-trifluoroethane
- Cas Number:
- 420-46-2
- Molecular formula:
- C2H3F3
- IUPAC Name:
- 1,1,1-trifluoroethane
Constituent 1
Study design
- Oxygen conditions:
- other: modeled
Results and discussion
% Degradation
- Parameter:
- probability of ready biodegradability (QSAR/QSPR)
- Remarks on result:
- not readily biodegradable based on QSAR/QSPR prediction
- Details on results:
- Biowin1: Does not biodegrade fast; Biowin2: Does not biodegrade fast; Biowin3: Weeks-months; Biowin4: Days-weeks; Biowin5: Biodegrades fast; Biowin6 Does not biodegrade fast.
Any other information on results incl. tables
Biowin1: Does not biodegrade fast; Biowin2: Does not biodegrade fast; Biowin3: Weeks-months; Biowin4: Days-weeks; Biowin5: Biodegrades fast; Biowin6 Does not biodegrade fast.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- valid model
- Interpretation of results:
- not inherently biodegradable
- Conclusions:
- The conclusion from the models is that HFC-143a will not undergo ready biodegradation
- Executive summary:
Biowin1: Does not biodegrade fast; Biowin2: Does not biodegrade fast; Biowin3: Weeks-months; Biowin4: Days-weeks; Biowin5: Biodegrades fast; Biowin6 Does not biodegrade fast. The conclusion from the models is that HFC-143a will not undergo ready biodegradation
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