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Environmental fate & pathways

Biodegradation in water: screening tests

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Administrative data

Endpoint:
biodegradation in water: screening tests
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Use of validated model
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6
Cross-reference
Reason / purpose:
reference to same study

Data source

Reference
Reference Type:
publication
Title:
Multimedia environmental models: the fugacity approach
Author:
Mackay, D.
Year:
2001
Bibliographic source:
Multimedia environmental models: the fugacity approach. 2nd ed. Lewis, Boca Raton, FL, USA

Materials and methods

Principles of method if other than guideline:
Biowin1:(linear Model Prediction, Biowin2 (Nonlinear model prediction), Biowin3 (Ultimate Biodegredation Timeframe), Biowin 4 (Promary Biodegredation Timeframe), Biowin5 (MITI Linear Model Prediction) and Biowin6 (MITI Non-linear Model Prediction).
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Study design

Oxygen conditions:
other: modeled

Results and discussion

% Degradation
Parameter:
probability of ready biodegradability (QSAR/QSPR)
Remarks on result:
not readily biodegradable based on QSAR/QSPR prediction
Details on results:
Biowin1: Does not biodegrade fast; Biowin2: Does not biodegrade fast; Biowin3: Weeks-months; Biowin4: Days-weeks; Biowin5: Biodegrades fast; Biowin6 Does not biodegrade fast.

Any other information on results incl. tables

Biowin1: Does not biodegrade fast; Biowin2: Does not biodegrade fast; Biowin3: Weeks-months; Biowin4: Days-weeks; Biowin5: Biodegrades fast; Biowin6 Does not biodegrade fast.

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Remarks:
valid model
Interpretation of results:
not inherently biodegradable
Conclusions:
The conclusion from the models is that HFC-143a will not undergo ready biodegradation
Executive summary:

Biowin1: Does not biodegrade fast; Biowin2: Does not biodegrade fast; Biowin3: Weeks-months; Biowin4: Days-weeks; Biowin5: Biodegrades fast; Biowin6 Does not biodegrade fast. The conclusion from the models is that HFC-143a will not undergo ready biodegradation