Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

1,1,1 -trifluoroethane is a gas with a boiling point of -47.4 deg C. It is therefore difficult to dissolve in water and will rapidly partition into the air. For that reason, aquatic toxicity studies were limited. It had a 96 -hr LC50 in trout of > 40mg/l (analytically measured), nominal 350 mg/l. EcoSar model v0.99 predicted 109 mg/l for fish. The 48 -hr EC50 for daphnia was determined to be 300 mg/l (analytically determined). EcoSar model v0.99 predicted the EC50 to be 115 mg/l for Daphnia. At the time 1,1,1-trifluoroethane was being studied, test methods did not exist to study the effects of such volatile materials on algae. Data on 1 -chloro-1,1 -difluoroethane was used as a read across substance. The EC50 was > 44 mg/l the highest level that could be tested due to evaporation of the test space into the head space above the medium. The EcoSar model v0.99 predicted the EC50 for 1,1,1-trifluoroethane to be 71 mg/l. As a final evaluation, data from 1,1,1,2 -tetrafluoroethane we used as read across for the effects on Pseudomonous putida. The 6 -hr EC50 was found to be > 730 mg/l, the highest level tested. In summary, data from trifluoroethane, chlorodifluoroethane and tetrafluoroethane indicate that trifluoroethane is not toxic.

Additional information

No additional information