Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
no hazard identified

Marine water

Hazard assessment conclusion:
no hazard identified

STP

Hazard assessment conclusion:
no hazard identified

Sediment (freshwater)

Hazard assessment conclusion:
no hazard identified

Sediment (marine water)

Hazard assessment conclusion:
no hazard identified

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
no hazard identified

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

Classification related key information

Biodegradation in water: 76 - 82% (ThOD) in 14 days (OECD 301 C)

Log Kow: -3.21 (handbook data)

Acute toxicity:

- to Fish: LC50 (96h) > 1000 mg/L for Oncorhynchus mykiss (OECD 203)

- to Aquatic invertebrates: EC50 (48h) > 220 mg/L for Daphnia magna (OECD 202)

- to Algae: ECr50 (72h) > 1000 mg/L, for Pseudokirchneriella subcapitata (OECD 201)

Chronic toxicity:

- to Fish: not available

- to Aquatic invertebrates: not available

- to Algae: NOEC (72h) ≥ 1000 mg/L for Pseudokirchneriella subcapitata (OECD 201)

 

Classification justification according to CLP

Based on the data above, glycine is considered rapidly biodegradable. The acute aquatic toxicity E(L)C50 values are > 1 mg/L for fish, invertebrates and algae. No long-term data are available for fish and aquatic invertebrates. The NOEC for the alga Desmodesmus subspicatus is >/= 1000 mg/L. Therefore, glycine is not classified as environmental hazard according to the Regulation (EC) No. 1272/2008 (CLP) and the Regulation (EU) No. 286/2011 (2ndATP).

 

Classification justification according to DSD

Based on the data above, glycine is considered to have a low potential for accumulation and is rapidly degradable. The acute aquatic toxicity E(L)C50 is > 100 mg/L for all trophic levels. Therefore, glycine is not classified as environmental hazard according to the Directive 67/548/EEC.