Registration Dossier
Registration Dossier
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EC number: 200-272-2 | CAS number: 56-40-6
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- no hazard identified
Marine water
- Hazard assessment conclusion:
- no hazard identified
STP
- Hazard assessment conclusion:
- no hazard identified
Sediment (freshwater)
- Hazard assessment conclusion:
- no hazard identified
Sediment (marine water)
- Hazard assessment conclusion:
- no hazard identified
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no hazard identified
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Conclusion on classification
Classification related key information
Biodegradation in water: 76 - 82% (ThOD) in 14 days (OECD 301 C)
Log Kow: -3.21 (handbook data)
Acute toxicity:
- to Fish: LC50 (96h) > 1000 mg/L for Oncorhynchus mykiss (OECD 203)
- to Aquatic invertebrates: EC50 (48h) > 220 mg/L for Daphnia magna (OECD 202)
- to Algae: ECr50 (72h) > 1000 mg/L, for Pseudokirchneriella subcapitata (OECD 201)
Chronic toxicity:
- to Fish: not available
- to Aquatic invertebrates: not available
- to Algae: NOEC (72h) ≥ 1000 mg/L for Pseudokirchneriella subcapitata (OECD 201)
Classification justification according to CLP
Based on the data above, glycine is considered rapidly biodegradable. The acute aquatic toxicity E(L)C50 values are > 1 mg/L for fish, invertebrates and algae. No long-term data are available for fish and aquatic invertebrates. The NOEC for the alga Desmodesmus subspicatus is >/= 1000 mg/L. Therefore, glycine is not classified as environmental hazard according to the Regulation (EC) No. 1272/2008 (CLP) and the Regulation (EU) No. 286/2011 (2ndATP).
Classification justification according to DSD
Based on the data above, glycine is considered to have a low potential for accumulation and is rapidly degradable. The acute aquatic toxicity E(L)C50 is > 100 mg/L for all trophic levels. Therefore, glycine is not classified as environmental hazard according to the Directive 67/548/EEC.
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