Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
grey literature
Title:
Parental toxicity
Year:
1980
Bibliographic source:
Journal of Medicinal Chemistry. Vol. 23, Pg. 1350

Materials and methods

Test material

Test animals

Species:
mouse

Administration / exposure

Route of administration:
intravenous

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
120 mg/kg bw

Applicant's summary and conclusion

Conclusions:
Mouse LD50 intravenous: 120mg/kg.
Executive summary:

Mouse LD50 intravenous: 120mg/kg.