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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Melting point / freezing point

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Administrative data

Link to relevant study record(s)

Referenceopen allclose all

Endpoint:
melting point/freezing point
Type of information:
other: Literature
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
As referenced in REACH Guidance Document 7a pg 28, “The use of Klimisch codes (Klimisch et al., 1997), can be extended to these secondary sources and a reliability code of (2) valid with restrictions should be assigned when using an authoritative secondary source.”
Deviations:
not specified
Remarks:
Guideline used not reported
Principles of method if other than guideline:
No details are provided in the reference concerning the method employed.
GLP compliance:
not specified
Melting / freezing pt.:
>= 35 - <= 38 °C
Conclusions:
35 to 38 degrees Celsius
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
As referenced in REACH Guidance Document 7a pg 29, “The use of Klimisch codes (Klimisch et al., 1997), can be extended to these secondary sources and a reliability code of (2) valid with restrictions should be assigned when using an authoritative secondary source.”
Deviations:
not specified
Remarks:
The guideline was not stated.
Principles of method if other than guideline:
No details are provided in the reference concerning the method employed.
GLP compliance:
not specified
Melting / freezing pt.:
37 °C
Conclusions:
37 deg Celsius
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
As referenced in REACH Guidance Document 7a pg 29, “The use of Klimisch codes (Klimisch et al., 1997), can be extended to these secondary sources and a reliability code of (2) valid with restrictions should be assigned when using an authoritative secondary source.”
Deviations:
not specified
Remarks:
No guideline is reported.
Principles of method if other than guideline:
No details are provided in the reference concerning the method employed.
GLP compliance:
not specified
Melting / freezing pt.:
312.15 K
Endpoint:
melting point/freezing point
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Deviations:
not applicable
Principles of method if other than guideline:
No details are provided in the reference concerning the method employed.
GLP compliance:
not specified
Type of method:
other: QSAR
Melting / freezing pt.:
37 °C
Remarks on result:
other: Experimental database

Description of key information

Based on information from several literature sources the melting point ranges from 35 -39°C. The mean value of 37°C was used for risk assessment.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
37 °C

Additional information