Registration Dossier
Registration Dossier
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EC number: 206-736-0 | CAS number: 371-41-5
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Prediction model
- Title:
- Hydrolysis by EPI (Estimation Programs Interface) Suite
- Author:
- Sustainability Support Service (Europe) AB - estimated
- Year:
- 2 011
- Bibliographic source:
- Estimation Programs Interface Suite™ United States Environmental Protection Agency, Washington, DC, USA. version 4.1
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: modelling database
- Principles of method if other than guideline:
- Data is from AopWin v1.92 programme of EPI suit estimation database
- GLP compliance:
- no
Test material
- Reference substance name:
- 4-fluorophenol
- EC Number:
- 206-736-0
- EC Name:
- 4-fluorophenol
- Cas Number:
- 371-41-5
- Molecular formula:
- C6H5FO
- IUPAC Name:
- 4-fluorophenol
- Test material form:
- solid: crystalline
- Details on test material:
- -Name of test material : 4-fluorophenol
- Molecular formula : C6H5FO
- Substance type: Organic
- Physical state: Solid
Constituent 1
- Radiolabelling:
- not specified
Study design
- Analytical monitoring:
- not specified
Duration of test
- Duration:
- 11.27 h
Results and discussion
- Preliminary study:
- The Hydrolysis rate constant of 4-fluorophenol was estimated to be 0.0000000000113892 cm3/molecule-sec. at half life of 11.270 Hrs.The estimated half life of the substance indicates that the substance is moderately hydrolysable.
- Transformation products:
- not specified
Any other information on results incl. tables
Atmospheric Oxidation (25 deg C) [AopWin v1.92]:
Hydroxyl Radicals Reaction:
OVERALL OH Rate Constant = 11.3892 E-12 cm3/molecule-sec
Half-Life = 0.939 Days (12-hr day; 1.5E6 OH/cm3)
Half-Life = 11.270 Hrs
Applicant's summary and conclusion
- Conclusions:
- The Hydrolysis rate constant of 4-fluorophenol was estimated to be 0.0000000000113892 cm3/molecule-sec. at half life of 11.270 Hrs.The estimated half life of 4-fluorophenol indicates that it is moderately hydrolysable.
- Executive summary:
The Hydrolysis rate constant of 4-fluorophenol was estimated to be 0.0000000000113892 cm3/molecule-sec. at half life of 11.270 Hrs.The estimated half life of 4-fluorophenol indicates that it is moderately hydrolysable.
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