Registration Dossier

Administrative data

Endpoint:
hydrolysis
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Prediction model
Title:
Hydrolysis by EPI (Estimation Programs Interface) Suite
Author:
Sustainability Support Service (Europe) AB - estimated
Year:
2011
Bibliographic source:
Estimation Programs Interface Suite™ United States Environmental Protection Agency, Washington, DC, USA. version 4.1

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: modelling database
Principles of method if other than guideline:
Data is from AopWin v1.92 programme of EPI suit estimation database
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: crystalline
Details on test material:
-Name of test material : 4-fluorophenol
- Molecular formula : C6H5FO
- Substance type: Organic
- Physical state: Solid
Radiolabelling:
not specified

Study design

Analytical monitoring:
not specified
Duration of test
Duration:
11.27 h

Results and discussion

Preliminary study:
The Hydrolysis rate constant of 4-fluorophenol was estimated to be 0.0000000000113892 cm3/molecule-sec. at half life of 11.270 Hrs.The estimated half life of the substance indicates that the substance is moderately hydrolysable.
Transformation products:
not specified

Any other information on results incl. tables

Atmospheric Oxidation (25 deg C) [AopWin v1.92]:

Hydroxyl Radicals Reaction:

OVERALL OH Rate Constant = 11.3892 E-12 cm3/molecule-sec

Half-Life = 0.939 Days (12-hr day; 1.5E6 OH/cm3)

Half-Life = 11.270 Hrs

Applicant's summary and conclusion

Conclusions:
The Hydrolysis rate constant of 4-fluorophenol was estimated to be 0.0000000000113892 cm3/molecule-sec. at half life of 11.270 Hrs.The estimated half life of 4-fluorophenol indicates that it is moderately hydrolysable.
Executive summary:

The Hydrolysis rate constant of 4-fluorophenol was estimated to be 0.0000000000113892 cm3/molecule-sec. at half life of 11.270 Hrs.The estimated half life of 4-fluorophenol indicates that it is moderately hydrolysable.