Registration Dossier

Administrative data

Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Study period:
25.10.2012 to 06.11.2012
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report Date:
2012

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other:
Principles of method if other than guideline:
Measurement of capacity of a compound to dissociate into respective ions.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material : 4-fluorophenol
-Molecular Formula: C6H5FO
-Molecular weight: 112.1
-Physical state:solid
- Substance type: Organic

Results and discussion

Dissociating properties:
yes
Dissosciation constantopen allclose all
No.:
#1
pKa:
0
Temp.:
27 °C
Remarks on result:
other: 0.00000536 (0.536 x10-5)
No.:
#2
pKa:
0
Temp.:
27 °C
Remarks on result:
other: 0.00000535(0.535 x 10-5)
No.:
#3
pKa:
0
Temp.:
27 °C
Remarks on result:
other: 0.00000532 (0.532 x 10-5)

Applicant's summary and conclusion

Conclusions:
The experimental pKa value for 4-fluorophenol was found to be 0.00000536,0.00000535,0.00000532 at 27 degC indicating that it has dissociation properties.The average pKa value at 27 Deg C is equivalent to 0.00000534333.
Executive summary:

The experimental pKa value for 4-fluorophenol was found to be 0.00000536,0.00000535,0.00000532 at 27 degC indicating that it has dissociation properties.The average pKa value at 27 Deg C is equivalent to 0.00000534333.