Registration Dossier

Environmental fate & pathways

Biodegradation in water and sediment: simulation tests

Administrative data

Endpoint:
biodegradation in water and sediment: simulation tests
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Prediction model
Title:
Biodegradation in water and sediment by Environmental Science Center’s PBT profiler
Author:
Environmental Science Center
Year:
2010
Bibliographic source:
PBT profiler, Office of Chemical Safety and Pollution Prevention , U.S. Environmental Protection Agency; version 1.301

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Modelling database
Principles of method if other than guideline:
PBT profiler database
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: crystalline
Details on test material:
-Name of test material : 4-fluorophenol
- Molecular formula : C6H5FO
- Substance type: Organic
- Physical state: Solid
Radiolabelling:
not specified

Study design

Oxygen conditions:
other: estimated database

Results and discussion

Mean total recoveryopen allclose all
Compartment:
other: water, material (mass) balance
% Recovery:
19
Compartment:
other: sediment, material (mass) balance
% Recovery:
0
% Degradationopen allclose all
% Degr.:
50
Parameter:
test mat. analysis
Sampling time:
38
% Degr.:
50
Parameter:
test mat. analysis
Sampling time:
340
Half-life of parent compound / 50% disappearance time (DT50)open allclose all
Compartment:
water
DT50:
38 d
Type:
other: estimated
Compartment:
sediment
DT50:
340 d
Type:
other: estimated
Transformation products:
not specified

Any other information on results incl. tables

Media

Half life

(days)

Percent in Medium

Water

38

19%

sediment

340

0%

Applicant's summary and conclusion

Conclusions:
Half life period of 4-fluorophenol in water was observed to be 38 days while in sediment it is 340 days.Based on these half life values of it is concluded that 4-fluorophenol is readily biodegradable in water where as it is non biodegradable in sediment. However, since there is no diffusion of the substance in the sediment as evident from the reported data (0% in sediment) and hence persistence in the sediment compartment is not likely to be critical.
Executive summary:

Based on level III fugacity model the half life period of 4-fluorophenol was estimated

Half life period of 4-fluorophenol in water was observed to be 38 days while in sediment it is 340 days.Based on these half life values of it is concluded that 4-fluorophenol is readily biodegradable in water where as it is non biodegradable in sediment. However, since there is no diffusion of the substance in the sediment as evident from the reported data (0% in sediment) and hence persistence in the sediment compartment is not likely to be critical.