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EC number: 908-343-6
CAS number: -
Table 1: Mean body weights of test animals in the male and female dose
Mean body weights ± S.D. (kg)
Days after administration
2.3 ± 0.15
2.12 ± 0.17
2.47 ± 0.21
2.3 ± 0.2
1.93 ± 0.12
2.25 ± 0.28
The acute dermal toxicity of a 35 % aqueous solution of hydrogen
peroxide was tested according to US EPA Guidelines (PB82 -232984, August
1982) and under GLP conditions. Male and female young adult New Zealand
White rabbits received a single dose of 2000 mg/kg the test material
under occlusion. Animals were prevented from manipulating the test site
by the application of Elizabethan collars. Occlusion remained for 24
hours. After removal of the occlusion, animals were observed for 14
days. None of the animals died so that the dermal LD50 value was greater
than 2000 mg/kg. All animals showed local skin irritation exhibiting
erythema, oedema and blanching of the test sites after 24 hours and
eschar and exfoliation at termination of the study. No gross internal
lesions were found at necropsy at termination of the study.
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