Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
dissociation constant
Data waiving:
study technically not feasible
Justification for data waiving:
other:
Justification for type of information:
JUSTIFICATION FOR DATA WAIVING
[Specific explanation in addition to field 'Justification for data waiving']

Determining the dissociation constant of the substance is technically not feasible as no method will work effectively for the following reasons:

1) The substance does not contain any chromophores so a spectrophotometric method will not be feasible.
2) The conductivity method is not feasible due to the low water solubility of the substance.
3) The potentiometric titration method will not be possible due to the overlapping pKa’s and the low water solubility.
4) The low water solubility will make it extremely difficult to quantify the substances pKa value even if a method was available.

Data source

Materials and methods

Test material

Constituent 1
Reference substance name:
Fatty acids, C14-C18 and C18 unsaturated, amides with 2,2’-iminodiethanol
EC Number:
948-052-1
Molecular formula:
not applicable as UVCB
IUPAC Name:
Fatty acids, C14-C18 and C18 unsaturated, amides with 2,2’-iminodiethanol
Test material form:
liquid

Results and discussion

Applicant's summary and conclusion