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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

Toxicity to microorganisms has been assessed for two substances that would fall within the MDI category definition. In both studies IC50 values were determined to be greater than the highest nominal loading rate, with NOEC values at the highest loading rate. Based on these results, members of the MDI category are not expected to be toxic to microorganisms at the limit of solubility.

Key value for chemical safety assessment

Additional information

Studies were performed to assess the toxicity of EC 406-370-3 and EC 445-760-8 in isolated form to microorganisms. The study conducted with EC 406-370-3 was designed to be compliant with the guideline 87/302/EEC. The microorganisms were exposed to the test item for 0.5 hours under aerobic conditions. The IC50 at the end of the test was greater than 100 mg/L and the NOEC was 100 mg/L, the highest test concentration. The study conducted with EC 445-760-8 was designed to be compliant with the OECD 209 guideline. The microorganisms were exposed to the test item for 3 hours under aerobic conditions. The derived IC50 at the end of the test were greater than 1000 mg/L and the NOEC was 1000 mg/L, the highest tested loading rate.