Registration Dossier

Administrative data

Endpoint:
explosive properties of explosives
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties
Justification for type of information:
The decomposition energy of the substance is less than 500J/g as determined by DSC-Measurement. See further information in the cross-ref.
Cross-reference
Reason / purpose:
data waiving: supporting information
Reference
Endpoint:
thermal stability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
22 - 23 March 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reference:
Composition 0
Qualifier:
according to
Guideline:
OECD Guideline 113 (Screening Test for Thermal Stability and Stability in Air)
Version / remarks:
1981
Deviations:
no
GLP compliance:
yes (incl. certificate)
Test material information:
Composition 1
Test substance thermally stable:
yes
Key result
Operating temp.:
>= 160 - <= 180 °C
Remarks on result:
other: endothermic effect
Key result
Operating temp.:
>= 180 - <= 300 °C
Remarks on result:
other: exothermic effect
Sublimation:
not determined
Transformation products:
not specified

In the temperature range of 160 – 180 °C an endothermic effect can be observed, directly followed by an exothermic effect in the temperature range of 180 – 300 °C, with an average decomposition energy of -400 J/g. No further thermal effects could be observed up to the maximum test temperature of 500 °C.

Conclusions:
The test item Adenosine-5'-monophosphate (AMP) (CAS no. 61-19-8) showed an exothermic effect in the temperature range of 180 – 300 °C with an average decomposition energy of approx. -400 J/g.
Executive summary:

The test item Adenosine-5'-monophosphate (AMP) (CAS no. 61-19-8) showed an exothermic effect in the temperature range of 180 – 300 °C with an average decomposition energy of approx. -400 J/g.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion