Registration Dossier

Administrative data

Endpoint:
surface tension
Type of information:
experimental study
Adequacy of study:
key study
Study period:
14 - 15 March 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report Date:
2017

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 115 (Surface Tension of Aqueous Solutions)
Version / remarks:
1995
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.5 (Surface Tension)
Version / remarks:
Regulation EC No. 440/2008
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
ring method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
impurity
Test material form:
solid: crystalline
Remarks:
crystalline powder
Details on test material:
Batch No: 11679700
Storage: at room temperature, protected from light

Results and discussion

Surface tension
Key result
Surface tension:
58.49 mN/m
Temp.:
20 °C
Conc.:
1.018 g/L
Remarks on result:
other: overall mean of first measurement (6 values measured) and second measurement (6 values measured) concentration refers to nominal concentration of the test item

Any other information on results incl. tables

The detailed results of two measurements are summarized in the table below.

 Value No. First measurement; approx. 1 day after preparation of the solution (mN/m) Second measurement; 55 min after the first measurement (mN/m)
 1  59.15 57.99
 2  59.13  57.93
 3  59.10  57.91
 4  59.07  57.89
 5  59.05  57.87
 6  59.02  57.85
Mean value of the individual values 59.09 +- 0.05  57.91 +- 0.05
Total mean value 58.49 +-0.58

Applicant's summary and conclusion

Conclusions:
According to OECD Test Guideline 115 and Regulation EC No. 440/2008 Part A Method A.5. the surface tension at 20°C of the test item Adenosine-5'-monophosphate (CAS no. 61-19-8) was determined to be 58.49 mN/m. According to Regulation EC No. 440/2008 Part A Method A.5. the test item is to be regarded as surface active material.
Executive summary:

According to OECD Test Guideline 115 and Regulation EC No. 440/2008 Part A Method A.5. the surface tension at 20°C of the test item Adenosine-5'-monophosphate (CAS no. 61-19-8) was determined to be 58.49 mN/m. According to Regulation EC No. 440/2008 Part A Method A.5. the test item is to be regarded as surface active material.