Registration Dossier

Administrative data

Endpoint:
thermal stability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
22 - 23 March 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report Date:
2017

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 113 (Screening Test for Thermal Stability and Stability in Air)
Version / remarks:
1981
Deviations:
no
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
impurity
Test material form:
solid: crystalline
Remarks:
crystalline powder
Details on test material:
Batch No: 11679700
Storage: at room temperature, protected from light

Results and discussion

For thermal stability study

Test substance thermally stable:
yes
Operating temperatureopen allclose all
Key result
Operating temp.:
>= 160 - <= 180 °C
Remarks on result:
other: endothermic effect
Key result
Operating temp.:
>= 180 - <= 300 °C
Remarks on result:
other: exothermic effect
Sublimation:
not determined
Transformation products:
not specified

Any other information on results incl. tables

In the temperature range of 160 – 180 °C an endothermic effect can be observed, directly followed by an exothermic effect in the temperature range of 180 – 300 °C, with an average decomposition energy of -400 J/g. No further thermal effects could be observed up to the maximum test temperature of 500 °C.

Applicant's summary and conclusion

Conclusions:
The test item Adenosine-5'-monophosphate (AMP) (CAS no. 61-19-8) showed an exothermic effect in the temperature range of 180 – 300 °C with an average decomposition energy of approx. -400 J/g.
Executive summary:

The test item Adenosine-5'-monophosphate (AMP) (CAS no. 61-19-8) showed an exothermic effect in the temperature range of 180 – 300 °C with an average decomposition energy of approx. -400 J/g.