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EC number: 206-596-0
CAS number: 355-93-1
The rate of hydrolysis of OFPMA as a function of pH was determined
according to a non-GLP OECD Guideline 111 study. While the extraction
method of the Tier 1 assessment was not reliable, the data did indicate
hydrolysis did occur within 5 days at 50°C and Tier 2 analysis was
The Tier 2 analysis employed a different analytical sample
preparation and analytical assessment method than Tier 1. The rate of
hydrolysis of OFPMA was found to be fast, with half lives of 2.7 days
for pH 4, 4.1 days for pH 7, and 3.9 hours for pH 9 at 20°C, using
second order kinetics.
The products of the hydrolysis were confirmed with NMR analysis to
be octafluoropentanol and methacrylic acid.
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