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EC number: 206-596-0
CAS number: 355-93-1
Some experimental studies have been conducted to investigate the
degradation of OFPMA in the environment.
OFPMA hydrolyses rapidly in water to octafluoropentanol and
methacrylic acid. The half lives of the OFPMA were reported to be 2.7
days for pH 4, 4.1 days for pH 7, and 3.9 hours for pH 9 at 25°C, using
second order kinetics according to the non-GLP OECD Guideline 111 study.
OFPMA is not readily biodegradable according to two GLP-compliant
OECD Guideline 310 studies. The minimum degradation reported was 22%
after 28 days. Compound analysis confirmed octafluoropentanol was a
biodegradation product of OFPMA. It was assumed the remaining portion of
the OFPMA biodegraded to methacrylic acid which would have be further
mineralized to carbon dioxide. The compound analysis did not detect
further mineralization of the octafluoropentanol during the 28-day study
The adsorption/desorption properties of OFPMA were predicted based
on the measured log Kow value. The regression method of Güsten and
Sabljic (1995) has predicted the log Koc value to be 2.60 (i.e., Koc =
394). According to ECHA (2017), substances with log Koc greater than 4
are generally regarded as highly adsorptive and likely to distribute to
sediment and soil. As the predicted Log Koc is less than 4, it is
unlikely that OFPMA will distribute to sediment and soil.
ECHA (2017). Guidance on Information Requirements and Chemical
Safety Assessment: Chapter R.11: PBT/vPvB assessment. Version 3.0, June
Güsten H, Sabljic A (1995). QSARS for Soil Sorption. In: EC.
Overview of Structure-Activity Relationships for Environmental
Endpoints: Part 1: General Outline and Procedures: Report of the
EU-DG-XII Project QSAR for Prediction of Fate and Effects of Chemicals
in the Environment. European Commission (EC), Belgium, Chapter III, p.
6-13, 25-27. EV5V-CT92-0211 - Part 1.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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