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EC number: 206-596-0
CAS number: 355-93-1
The following data show that the cell concentration of the control
cultures increased by a factor of 27 after 72 hours. This increase was
in line with the OECD Guideline that states the enhancement must be at
least by a factor of 16 after 72 hours.
Mean cell density of control at 0 hours: 3.97 x 10³ cells per mL
Mean cell density of control at 72 hours: 1.06 x 10E5 cells per mL
The mean coefficient of variation for section by section specific
growth rate for the control cultures was 35% and hence satisfied the
validation criterion given in the OECD Guideline which states the mean
must not exceed 35%.
The coefficient of variation for average specific growth rate for
the control cultures over the test period (0 - 72 h) was 2% and hence
satisfied the validation criterion given in the OECD Guideline which
states that this must not exceed 7%.
A GLP-compliant study according to OECD Guideline 201 was
conducted to assess the acute toxicity of octafluoropentyl methacrylate
to freshwater algae. Following range-finding tests, Desmodesmus
subspicatus was exposed to dilutions of a 100% v/v saturated solution of
test item with geometric mean measured concentration of 0.029, 0.054,
0.24, 0.53, and 4.9 mg/L for 72 hours.
The 72-hour lowest observed effect concentration (LOEC) for both
growth rate and yield was the 100% v/v saturated solution with a
geometric mean measured concentration of 4.9 mg/L. The 72-hour EC50
(growth rate) based on the geometric mean measured test concentrations
was 4.4 mg/L and correspondingly the No Observed Effect Concentration
was 0.53 mg/L (for both growth rate and yield).
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