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EC number: 206-596-0
CAS number: 355-93-1
Experimental studies were conducted to determine the
ecotoxicological effects of OFPMA; specifically:
embryo toxicity (OECD Guideline 236);
daphnia toxicity (OECD Guideline 202);
daphnia toxicity (OECD Guideline 211) of both OFPMA and its degradation
algae inhibition (OECD Guideline 201); and
sludge respiration inhibition (OECD Guideline 209).
The fish embryo toxicity (FET) study results were further
supported by nine QSAR 96-hour acute fish toxicity predictions.
A review of the ecotoxicological data set as a whole as identified
algae to be the most sensitive aquatic species with a measured 72-hour
algae EC50 value of 4.4 mg/L. Therefore, further aquatic vertebrate
testing of OFPMA is not necessary to address the regulatory requirement.
Also, the chronic daphnia toxicity results of the OFPMA
degradation product octafluoro-1-pentanol, which report a 21-day NOEC of
73 mg/L, the highest concentration tested, indicate that there is no
chronic toxicity concern.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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