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EC number: 269-950-3
CAS number: 68391-42-4
concentration oftest substance(% w/v)
number oflymph nodesassayed
cpm perlymph node(×10-2)
0 (vehicle only)
sensitisation potential of the test substance was assessed based on OECD
guideline 429 (local lymph node assay). Male CBA/Ca mice were exposed to
test substance at concentrations of 0, 3, 10 and 30 % in acetone.
Isotope (3H-methyl thymidine) incorporation was measured in lymph nodes.
The negative (vehicle alone) and positive (hexylcinnamaldehyde at
concentrations of 1, 3, and 10 % w/v in acetone) controls were tested.
and negative controls were valid. The isotope incorporation was
increased by less than a threefold at all concentrations of test
substance. Under test conditions, test substance was considered to be
not sensitizing to mouse skin.
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