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EC number: 269-950-3 | CAS number: 68391-42-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Short-term toxicity to aquatic invertebrates
EC50 (48 h) = 18.6 mg/l (nominal concentration)
Toxicity to aquatic algae and cyanobacteria
ErC50> 100 mg/l (loading rate value)
EyC50 > 100 mg/l (loading rate value)
Additional information
Aquatic toxicity of target substance was assessed based on a read across approach, using available data on Similar Substance 01. Details on the read across are reported in section 13.
Both target substance and read across substance are not ready biodegradable and have a low solubility, below 20 mg/l in water.
Short-term toxicity to aquatic invertebrates
Similar Substance 01 was tested for acute toxicity to daphnia magna in a 48 -hour static test according to OECD guideline 202.
Nominal concentrations tested were 100 %, 50 %, 25 %, 12.5 %, 6.25 % of a saturated solution with nominal loading of 100 mg/l. Measured concentrations 0 -hour and 48 -hour after start of exposure were below the lowest calibration level, thus nominal value were used. At nominal concentration of 25 mg/l, 18/20 were found to be immobile; at higher concentrations all daphnids were immobile.
Based on nominal concentrations, the EC50 value was calculated as 18.6 mg/l after 48 hours.
Toxicity to aquatic algae and cyanobacteria
Similar Substance 01 was tested on toxicity to aquatic algae and cyanobacteria in a 72 -hour static test according to OECD guideline 201.
A saturated solution with a nominal loading of 100 mg test substance/l was prepared and undissolved particles were removed by membrane filtration. Components of dilution water were added to the saturated solution. Concentrations used in the test were 6.25 - 12.5 - 25.0 - 50.0 - 100 % of the saturated solution. Three replicates were tested for each concentration and six replicates for the control. Test media were clear throughout the test period. Analytical monitoring of test solutions was done via HPLC‑DAD at 0 h and recovery rates were found to be below the lowest calibration level (LCL). Therefore, all effect values were referred to nominal loading levels. After 72 h, growth rate inhibition at the highest loading level was only 6 % (not significant) and yield inhibition was 28 %. Thus,
- growth rate: ErC50 (72h) > 100 % (i.e. 100 mg/l nominal loading).
- yield: EyC50 (72h) > 100 % (i.e. 100 mg/l nominal loading).
Justification for classification or non-classification
According to the CLP Regulation (EC 1272/2008), the threshold of classification of a substance for acute aquatic toxicity is 1 mg/l. This limit is compared with LC50 (96h) for fish, EC50 (48 h) for daphnia and EC50 (72 - 96 h) for algae or aquatic plants.
As for chronic toxicity, in case of lack of chronic data, the toxic potential is identified by appropriate combinations of acute toxicity data and lack of biodegradability. The threshold of classification is 100 mg/l.
In case of poorly soluble substances, the threshold for classification is identified as the solubility limit of the substance.
Based on EC50 values obtained, no classification for acute toxicity was applied; based on EC50 (48h) of 18.6 mg/l for immobilisation effects in daphnids, the substance is classified as Aquatic Chronic Toxicity 3 for chronic toxicity according to the CLP Regulation (EC 1272/2008).
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