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EC number: 203-214-4
CAS number: 104-57-4
The skin sensitising potential of the test
item was tested in a open epicutaneous test with guinea pigs. The test
was conducted on groups of at least 6 male and female animals weighing
300 - 450 g. Daily applications were made for 3 weeks to a clipped 8 cm²
area on the flank of each guinea pig. The test sites were not covered
and the reactions were read 24 hours after each application. A total of
21 applications of 0.1 mL test material in an unspecified vehicle were
made for 21 days. The 10 controls were either left untreated or treated
with 0.1 mL test material in an unspecified vehicle for 21 days. At the
challenge phase, both the test and control animals were treated at some
lower primary non-irritating concentrations. At a test concentration of
10 % no sensitising effect were observed.
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