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EC number: 203-214-4
CAS number: 104-57-4
In a human maximisation study, the test
material was applied under occlusion to the volar forearm of 25 healthy
male subjects for five alternate-day 48 -hour periods. The patch sites
were pre-treated for 24 hours with 5 % aqueous sodium lauryl sulfate
under occlusion. Following a ten-day rest period challenge patches of
all materials were applied under occlusion to fresh sites for 48 hours.
Challenge applications were preceded by one-hour application of 10 %
aqueous sodium lauryl sulfate under occlusion. The challenge sites were
read on removal of the patch and 24 hours thereafter. No sensitisation
was found after 48 and 72 hours.
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