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EC number: 203-313-2
CAS number: 105-60-2
As acute test on fish as well as acute and chronic test on algae and invertebrates reveal a low hazard potential of epsilon-Caprolactam, a chronic fish study is scientifically unjustified. Therefore, and for reasons of animal welfare, a long-term toxicity study in fish is not provided.
In Annex IX of Regulation (EC) No 1907/2006, it is laid down that
chronic tests shall be proposed by the registrant if the chemical safety
assessment indicates the need to investigate further the effects on fish.
According to Annex I of this regulation, the chemical safety assessment
triggers further action when the substance or the preparation meets the
criteria for classification as dangerous according to Directive
67/548/EEC or Directive 1999/45/EC or is assessed to be a PBT or vPvB.
The hazard assessment of e-caprolactam reveals neither a need to
classify the substance as dangerous to the environment, nor is it a PBT
or vPvB substance, nor are there any further indications that the
substance may be hazardous to the environment. Therefore, and for
reasons of animal welfare a chronic test on fish is not provided.
Furthermore, respective exposure scenarios are not calculated.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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