Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Ammonium hydrogendifluoride is listed on Annex I of Directive 67/548/EEC with classification as Corrosive (R34) 'Causes burns'.  Further testing for the irritant and corrosive effects of this substance is therefore not required and cannot be justified either scientifically or on animal welfare grounds.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (corrosive)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

No data are available: waivers are proposed for skin irritation and eye irritation endpoints based on the existing R34 classification of the substance. The substance dissolves readily in aqueous (i.e. physiological) environments to produce hydrofluoric acid which is likely to be responsible for the corrosive effects.


Effects on skin irritation/corrosion: corrosive

Effects on eye irritation: highly irritating

Justification for classification or non-classification

Ammonium hydrogendifluoride is listed on Annex I of Directive 67/548/EEC with classification as Corrosive (R34) 'Causes burns'. No change to the existing classification is proposed.