Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
215-676-4
CAS no.:
1341-49-7
Index number:
Molecular formula:
F2H5N
SMILES:
[NH4+].F.[F-]
InChI:
InChI=1S/2FH.H3N/h2*1H;1H3
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
12
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is toxic if swallowed and causes severe skin burns and eye damage.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance is fatal in contact with skin, is toxic if inhaled and causes serious eye damage.

Breakdown of all 3062 C&L notifications submitted to ECHA

Acute Tox. 3 H301 Harmonised Classification
Skin Corr. 1B H314 Harmonised Classification
Eye Dam. 1 H318
Acute Tox. 1 H310
Acute Tox. 3 H331
STOT RE 1 H372
STOT SE 3 H335
Eye Irrit. 2 H319
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 10 active registrations under REACH, 2 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 1 000 - 10 000 tonnes per year.

This substance is used by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

This substance is used in the following products: non-metal-surface treatment products and washing & cleaning products.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: roller or brushing applications, industrial spraying, laboratory work and hand mixing with intimate contact only with personal protective equipment available.

Other release to the environment of this substance is likely to occur from: indoor use as reactive substance and outdoor use as reactive substance.

This substance is used in the following products: metal surface treatment products, non-metal-surface treatment products and washing & cleaning products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, mixing in open batch processes and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: non-metal-surface treatment products, metal surface treatment products and washing & cleaning products.

This substance is used in the following areas: mining and building & construction work.

This substance is used in the following activities or processes at workplace: industrial spraying, treatment of articles by dipping and pouring, greasing at high energy conditions, roller or brushing applications and hand mixing with intimate contact only with personal protective equipment available.

Release to the environment of this substance can occur from industrial use: as processing aid and in processing aids at industrial sites. Other release to the environment of this substance is likely to occur from: indoor use as reactive substance and outdoor use as reactive substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, mixing in open batch processes and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not breathe the dust, fume, gas, mist, vapours or spray; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If exposed or you feel unwell: call a poison center or doctor/physician. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If swallowed: rinse mouth. Do not induce vomiting. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • ALTICHEM, 4 Rue Jacques Vaucanson 95310 SAINT-OUEN-L'AUMÔNE VAL D'OISE France
  • Bollig & Kemper GmbH & Co. KG, Vitalisstraße 114 D-50827 Köln Germany
  • DERIVADOS DEL FLÚOR, S.A.U., Ontón 39706 Castro Urdiales Cantabria Spain
  • INTERTEK FRANCE, ZAC Ecoparc II 27400 HEUDEBOUVILLE France
  • likedeelers GmbH, Hallbergstr. 10 40239 Düsseldorf Germany
  • NPM Silmet OÜ, Kesk tn. 2 40231 Sillamäe Ida- Virumaa Estonia
  • REACHLaw Ltd, Vänrikinkuja 3 JK 21 FI-02600 ESPOO helsinki Finland
  • sapi impianti srl, Z.I. loc. Il Piano 53031 casole d'Elsa (SI) Italy
  • Solvay Fluor GmbH, Hans-Boeckler-Allee 20 30173 HANNOVER Germany
  • Wegochem Europe B.V., Bredaseweg 108a 4902 NS Oosterhout Netherlands
  • Arcerion GmbH, Gabrielenstr. 15 80636 München Germany
  • Chemetall Kft., org. složka, Počernická 96 108 00 Praha 10 Czech Republic

Substance names and other identifiers

ammonium bifluoride
C&L Inventory
ammonium hydrogen difluoride
C&L Inventory
Ammonium hydrogendifluoride
EC Inventory, REACH pre-registration
ammonio bifluoruro (it)
C&L Inventory
Ammoniumbifluorid (de)
C&L Inventory
Ammoniumbifluoridi (fi)
C&L Inventory
Ammoniumhydrogendifluorid (de)
C&L Inventory
ammoniumhydrogenfluorid (da)
C&L Inventory
ammoniumvätedifluorid (sv)
C&L Inventory
ammoniumvätefluorid (sv)
C&L Inventory
ammoniumwaterstofdifluoride (nl)
C&L Inventory
Ammooniumbifluoriid (et)
C&L Inventory
Ammooniumvesinikdifluoriid (et)
C&L Inventory
ammónium-bifluorid (hu)
C&L Inventory
ammónium-hidrogén-difluorid (hu)
C&L Inventory
amonija difluorīds (lv)
C&L Inventory
amonija hidrogēndifluorīds (lv)
C&L Inventory
amonijev bifluorid (hr)
C&L Inventory
amonijev hidrogendifluorid (sl)
C&L Inventory
amonijev vodikov difluorid (hr)
C&L Inventory
amonio bifluoridas (lt)
C&L Inventory
amonio vandenilio difluoridas (lt)
C&L Inventory
bifluoreto de amónio (pt)
C&L Inventory
bifluorure d'ammonium (fr)
C&L Inventory
bifluoruro d'ammonio (it)
C&L Inventory
difluorid monoamónny (sk)
C&L Inventory
difluorura acida de amoniu (ro)
C&L Inventory
difluorura de amoniu (ro)
C&L Inventory
difluoruro de amonio (es)
C&L Inventory
fluorek amonu-fluorowodór(1/1) (pl)
C&L Inventory
hidrogenodifluoreto de amónio (pt)
C&L Inventory
hydrogendifluorid amonný (cs)
C&L Inventory
hydrogendifluorid amónny (sk)
C&L Inventory
kwaśny fluorek amonu (pl)
C&L Inventory
Wodorofluorek amonu (pl)
C&L Inventory
διφθοριούχο αμμώνιο (el)
C&L Inventory
διφθοριούχο υδρογόνο αμμώνιο (el)
C&L Inventory
амониев бифлуорид (bg)
C&L Inventory
амониев хидроген дифлуорид (bg)
C&L Inventory
Ammonium fluoride ((NH4)(HF2))
Other
AMBI
Registration dossier
ammonium fluoride
C&L Inventory
ammonium fluoride hydrofluoride
C&L Inventory, Registration dossier
ammonium fluoride hydrofluoride (1:1:1)
C&L Inventory
ammonium hydrofluoride fluoride
C&L Inventory, Other
Ammonium hydrogen fluoride
C&L Inventory
Ammonium hydrogenfluoride
C&L Inventory
ammonium-hydrogendifluoride-
C&L Inventory
azanium fluoride hydrofluoride
C&L Inventory
cadmium
C&L Inventory
Nano grip
C&L Inventory
009-009-00-4
Index number
C&L Inventory
120144-37-8
Deleted CAS number
Other
1257076-06-4
Deleted CAS number
Other
127026-25-9
Deleted CAS number
Other
1341-49-7
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other
135446-53-6
Deleted CAS number
Other
14055-61-9
Deleted CAS number
Other
159431-44-4
Deleted CAS number
Other
1628788-89-5
Deleted CAS number
Other
16941-26-7
Deleted CAS number
Other
19121-60-9
Deleted CAS number
Other
52697-21-9
Deleted CAS number
Other
7790-15-0
Deleted CAS number
Other
96740-33-9
Deleted CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [2]
C Form
Crystalline (100%) [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Melting/freezing point

Study results
  • 2 studies submitted
  • 1 study processed
R Melting / freezing point
125.6 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
125.85 °C

Boiling point

Study results
  • 2 studies submitted
  • 2 studies processed
R Boiling point
239.5 - 240 °C [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
239.85 °C

Density

Study results
  • 2 studies submitted
  • 2 studies processed
R Density
1.5 g/cm³ [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
1 500

Vapour pressure

Study results
  • 1 study submitted
  • 1 study processed
R Vapour pressure
1.08 Pa @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
1.08 Pa @ 19.85 °C

Partition coefficient

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 1 study submitted
  • 1 study processed
R Water solubility (mass/vol.)
602 g/L @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
602 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 1 study processed
C Dissociating properties
Yes (100%) [1]
R Dissociation constant
6.39 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
pKa at 20 °C
6.3

Viscosity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 1.3 mg/L (1)
Intermittent releases (freshwater) -
Marine water -
Intermittent releases (marine water) -
Sewage treatment plant (STP) 76 mg/L (1)
Sediment (freshwater) -
Sediment (marine water) -
Hazard for Air
Air -
Hazard for Terrestrial Organism
Soil 22 mg/kg soil dw (1)
Hazard for Predators
Secondary poisoning -

Short–term toxicity to fish

Study results
  • 13 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 421.4 mg/L [1]
LC0 (4 days) 316 mg/L [1]
LC100 (4 days) 562 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 12
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
LC50 for freshwater fish
422 mg/L

Long–term toxicity to fish

Study results
  • 5 studies submitted
  • 4 studies processed
P/RResults
NOEC (61 days) 1.2 mg/L [1]
NOEC (31 days) 48 µg/L [1]
LOEC (73 days) 22 µg/L [1]
LOEC (33 days) 50 µg/L [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 1 4
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater fish
4 mg/L

Short–term toxicity to aquatic invertebrates

Study results
  • 6 studies submitted
  • 3 studies processed
P/RResults
EC50 (4 days) 26 - 48 mg/L [1]
LC50 (10 days) 455 - 13 800 µg/L [7]
LC50 (48 h) 101 mg/L [1]
EC0 (48 h) 39.7 mg/L [1]
LOEC (48 h) 74 mg/L [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 5
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for freshwater invertebrates
26 mg/L

Long–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater invertebrates
8.9 mg/L

Toxicity to aquatic algae and cyanobacteria

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (18 days) 2.7 g/L [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
43 mg/L
EC50 for marine water algae
81 mg/L
EC10 or NOEC for freshwater algae
50 mg/L
EC10 or NOEC for marine water algae
50 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
NOEC (3 h) 510 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence 1
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for microorganisms
3.126 g/L

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (5.133 months) 750 - 1 200 mg/kg soil dw [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Long-term EC10 / LC10 / NOEC
1.2 g/kg soil dw

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (4.2 months) 800 mg/kg bw [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Long-term EC10 / NOEC
106 mg/kg soil dw

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 2.3 mg/m³ repeated dose toxicity
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: (DNEL) 3.8 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: - -
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
EYE Exposure
-
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 45 µg/m³ repeated dose toxicity
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: - -
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 15 µg/kg bw/day repeated dose toxicity
Acute /short term: - -
EYE Exposure
-

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 1 study submitted
  • 1 study processed
P/RResults
LD50 130 mg/kg bw (rat) [1]
LDLo 100 - 147 mg/kg bw (rat) [2]
M/CInterpretations of results
Toxic [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (corrosive)
Eye
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 6 studies submitted
  • 4 studies processed
P/RResults
NOAEL (rat): 100 ppm [2]
NOEL (rat): 30 - 200 ppm [4]
NOEL (mouse): 50 - 400 ppm [4]
LOEL (mouse): 50 ppm [1]

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study
Weight of evidence 6
Other
Data waiving
no waivers
Study data: inhalation
  • 8 studies submitted
  • 7 studies processed
P/RResults
NOAEL (rat): 0.88 - 1 ppm [2]
LOAEL (rat): 105 - 175 mg/m³ air [2]
NOEL (pig): 61 ppm [1]
LOEL (guinea pig): 119 mg/m³ air [1]
LOEL (pig): 103 ppm [1]

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence 8
Other
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 1 1
Supporting study 1
Weight of evidence 5
Other
Data waiving
no waivers
Study data: in vivo
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study 3
Weight of evidence 2
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence 2
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 2
Supporting study 1 4
Weight of evidence
Other 5
Data waiving
no waivers
Study data: developmental
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study
Supporting study
Weight of evidence 8
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant