Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1988
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Test procedure according to national standard but without GLP. Exposure time only 24 hours; results taken from literature

Data source

Reference
Reference Type:
review article or handbook
Title:
BUA Report 85, Ref. Rhône-Poulenc, 1991b
Author:
Beratergremium für umweltrelevante Altstoffe der Gesellschaft Deutscher Chemiker (BUA)
Year:
1992
Bibliographic source:
Hirzel Verlag, Stuttgart

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
ISO 6341 (Water quality - Determination of the Inhibition of the Mobility of Daphnia magna Straus (Cladocera, Crustacea))
Deviations:
no
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Sampling and analysis

Analytical monitoring:
no

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
24 h

Results and discussion

Effect concentrationsopen allclose all
Duration:
24 h
Dose descriptor:
EC50
Effect conc.:
< 0.36 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Remarks on result:
other: (65% immobile daphnids at 0.36 mg/L)
Duration:
24 h
Dose descriptor:
EC100
Effect conc.:
0.72 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Remarks:
24-h EC50 in a reference test with potassium dichromat was 1.0 mg/L (the results of inter laboratory tests and a Technical Corrigendum to ISO 6341 give an EC50-24 h of the potassium dichromate (K2Cr2O7) within the range 0.6 mg/L to 2.1 mg/L)
Conclusions:
The 48h-EC50 determined in this study was < 0.36 mg/L
Executive summary:

In a 24-h toxicity study, daphnids (Daphnia magna) were exposed toChloranil (2,3,5,6-tetrachloro-1,4-benzoquinone)at nominal concentrations of 0 (control), 0.36 and 0.72 mg/L under static conditions in accordance ISO 6341. The test material was delivered to the testing laboratory as a solution (nominal 0.72 mg/L in testing water) and no analytical monitoring was performed. The basis for effect was immobilization. The 24-hour EC50 was <0.36 mg/L. At 0.36 mg/L, immobilization amounted to 65%. The 24-hour EC100 based on immobilization was 0.72 mg/L.