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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature
Qualifier:
no guideline followed
Principles of method if other than guideline:
The partition coefficient of the test material was determined at room temperature, reported was a temperature of 20 °C. No further details about the methods used have been specified in this review.
GLP compliance:
no
Type of method:
other: no data
Partition coefficient type:
octanol-water
Type:
log Pow
Partition coefficient:
-2.28
Remarks on result:
other: no temperature reported
Conclusions:
The log Pow of methylphosphonic acid was reported to be -2.28.

Description of key information

Based on an expert statement the log Pow was estimated to -1.5559 at a pH of 4.

Key value for chemical safety assessment

Log Kow (Log Pow):
-1.556
at the temperature of:
20 °C

Additional information

Based on an expert statement the Partition Coefficient (logPow) was estimated for MPA. From this calculation resulted a log Pow of -1.5559 (at a pH of 4) which shall be used for risk assessment. As supporting information, the log D was calculated for the substance methyl phosphonic acid by using the SPARC on-line calculator (for getting log Pow estimates covering the whole pH range). These calculated results, which unanimously are indicating the very low log Pow of the test tem, are further supported by a log Pow of -2.28 as actually measured for the test item (reliability of this study not assignable).