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EC number: 218-658-4 | CAS number: 2212-32-0
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 30/03/2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- GLP study performed using an accepted method
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: vapour pressure balance
- Specific details on test material used for the study:
- Appearance/Physical State: Yellow liquid
Batch: 1721964
Purity: 99.0%
Expiry Date: 08 April 2016
Storage Conditions: Room temperature in the dark - Key result
- Temp.:
- 25 °C
- Vapour pressure:
- ca. 57.5 Pa
- Key result
- Transition / decomposition:
- no
- Remarks:
- The test item did not change in appearance under the conditions used in the test
- Conclusions:
- The vapor pressure of the test item has been determined to be 58 Pa at 25 ºC.
- Executive summary:
The vapour pressure of 2-[[2-(Dimethylamino)ethyl]methylamino]ethanol (CAS: 2212-32-0) was determined to be 58 Pa at 25 °C, using the vapour pressure balance method, designed to be compatible with Method A4 Vapour Pressure of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 104 of the OECD Guidelines for Testing of Chemicals, 23 March 2006.
Reference
Recorded temperatures, mass differences and the resulting calculated values of vapour pressure are as follows:
Temp. (ºC) |
Temp. (K) |
Reciprocal temp. (K-1) |
Mass difference (μg) |
Mass difference (kg) |
Vapour pressure (Pa) |
Log10 Vp |
-25 |
248.15 |
0.004029821 |
176.81 |
1.768E-07 |
0.245457578 |
-0.610023555 |
-24 |
249.15 |
0.004013646 |
203.43 |
2.034E-07 |
0.282412958 |
-0.549115380 |
-23 |
250.15 |
0.003997601 |
221.94 |
2.219E-07 |
0.308109581 |
-0.511294797 |
-22 |
251.15 |
0.003981684 |
258.81 |
2.588E-07 |
0.359294587 |
-0.444549326 |
-21 |
252.15 |
0.003965893 |
299.61 |
2.996E-07 |
0.415935440 |
-0.380974074 |
-20 |
253.15 |
0.003950227 |
340.28 |
3.403E-07 |
0.472395819 |
-0.325693955 |
-19 |
254.15 |
0.003934684 |
433.02 |
4.330E-07 |
0.601142699 |
-0.221022423 |
-18 |
255.15 |
0.003919263 |
427.71 |
4.277E-07 |
0.593771059 |
-0.226380974 |
-17 |
256.15 |
0.003903963 |
467.14 |
4.671E-07 |
0.648510001 |
-0.188083322 |
-16 |
257.15 |
0.003888781 |
530.55 |
5.306E-07 |
0.736539326 |
-0.132804060 |
-15 |
258.15 |
0.003873717 |
588.28 |
5.883E-07 |
0.816683356 |
-0.087946295 |
Data are only provided for Run 1
A plot of Log10 (vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 1 gives the following statistical data using an unweight least squares treatment.
Slope: -3.40 x 103
Standard error in slope: 135
Intercept: 13.1
Standard error in intercept: 0.533
The results obtained indicate the following vapour pressure relationship:
Log10 (Vp (Pa)) = -3.40 x 103 / temp(K) + 13.1
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of 1.70.
The values of vapour pressure at 25 °C extrapolated from of the six determinations are summarized below:
Run |
Log10 Vp at 25 ºC |
Vapour pressure (Pa) |
1 |
1.70 Pa |
50.1 |
2 |
1.76 Pa |
57.5 |
3 |
1.81 Pa |
64.6 |
4 |
1.78 Pa |
60.3 |
5 |
1.72 Pa |
52.5 |
6 |
1.79 Pa |
61.7 |
Mean |
1.76 Pa |
57.5 |
Description of key information
The vapour pressure of 2-[[2-(Dimethylamino)ethyl]methylamino]ethanol (CAS: 2212-32-0) was determined to be 58 Pa at 25 °C, using the vapour pressure balance method, designed to be compatible with Method A4 Vapour Pressure of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 104 of the OECD Guidelines for Testing of Chemicals, 23 March 2006.
Key value for chemical safety assessment
- Vapour pressure:
- 58 Pa
- at the temperature of:
- 25 °C
Additional information
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