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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

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Administrative data

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Description of key information

An experimental screening biodegradability test (OECD 301D, non-GLP, Klimisch 2) indicates the substance is not readily biodegradable.
A QSAR modelling (BIOWIN, Klimisch 2) however predicts ready biodegradability.

Key value for chemical safety assessment

Biodegradation in water:
inherently biodegradable, not fulfilling specific criteria

Additional information

The test substance was not readily degradable in the screening non-GLP test with OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test). Therein the test substance was not inhibitory at 2.3 mg/L nominal concentration to microorganisms. The result is considered as valid with restrictions (Klimisch 2).

Remark: the 2.3 mg/L nominal concentration was not analytically verified (highly exceeds the water solubility of the test substance), and the form of the test material in the solution may vary (dissolved, suspended, emulsified). However, in principle the OECD 301D method is suitable for poorly water soluble, volatile and adsorptive substances.

The test substance was estimated to be readily biodegradable by BIOWIN 4.10 QSAR modelling. The model is recognised by the ECHA Guidance R.6 on QSARs and grouping of substances, May 2008. The result of the QSAR modelling is considered as valid, and is rated as reliable with restrictions (Klimisch 2) and used as weight of evidence for classification and labelling.