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Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

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Description of key information

LC50 >1250 mg a.i./kg d.w., NOEC 1250 mg a.i./kg d.w., Eisena fetida, 14 days, OECD 207, Palmers & Beavers 1996a.

Key value for chemical safety assessment

Long-term EC10, LC10 or NOEC for soil macroorganisms:
1 250 mg/kg soil dw

Additional information

The toxicity to soil macroorganisms was determined in an acute toxicity study using the earthworm (Eisena fetida). The study was performed according to GLP and in line with the standardised guideline OECD 207. Worms were exposed to the test material for 14 days at the following nominal concentrations: 162, 270, 450, 750 and 1250 mg a.i./kg dry soil. Artificial soil was used as the substrate. A solvent control was run concurrently for comparison.

Under the conditions of the test, no mortalities were observed in any of the exposure groups. All worms appeared normal in appearance and behaviour throughout the study. Average group body weight measurements showed no apparent treatment-related effects and there were no statistically significant differences (p>0.05) observed in body weight change among worms in the treatment groups when compared to the controls. On Day 0, all worms were either beneath the soil surface or in the process of burrowing by the ¾ hour observation interval. On Day 7 all worms had burrowed by 3½ hours following replacement on the soil surface following observations for mortality. No mortalities were observed in the controls over the 14 day test period and all control worms appeared normal in appearance and behaviour throughout the test.

The 14 day LC50 was determined to be >1250 mg a.i./kg dry soil, the highest concentration tested. The NOEC was determined to be 1250 mg a.i./kg dry soil.

The study was performed to a high standard, in line with GLP and standardised guidelines. Accordingly, the study has been assigned a reliability score of 1 in line with the principles for assessing data quality set out in Klimisch (1997). The available data are deemed to be relevant, reliable and adequate for the purposes of risk assessment.