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EC number: 253-057-0
CAS number: 36483-57-5
FR-513 was instilled into the test eyes of 3 NZ white rabbits at a dose
of 84.6, 84.8 or 84.7 mg. Each eye was held closed for approx. 1 sec
after administration. Observations were made 1, 24, 48 and 72 hours and
7, 14 and/or 21 after instillation.
Under the conditions of the study FR-513 was found to have effects on
the eyes of the rabbits, which completely resolved after 7 or 14 days in
In one animal some of the effects persisted until 21 days (maximum
Based on the study results, FR-513 is classified as irritating to eyes
in the EU.
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