Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 253-057-0
CAS number: 36483-57-5
See attached document on tables
A study was performed to assess the potential of the test material to
induce DNA repair in isolated rat hepatocytes following in vivo
administration. The method used has been designed to comply with the
relevant guidelines such as OECD 486.
The study resulted in no marked increases in the incidence of
unscheduled DNA synthesis in animals dosed with the test material at
either time point. Both positive and negative controls produced marked
increases in the incidence of cells in repair and the vehicle control
groups gave acceptable values for net nuclear grain counts. Therefore
the test material was considered to be non-genotoxic under the
conditions of the study.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again