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EC number: 205-381-9
CAS number: 139-89-9
inter-tissue variability in viability between two tissues and the
maximum difference in percentage between the mean viability of two
tissues and one of the two tissues treated with HEDTA-H3 were above the
acceptability criteria (up to 44 and 22%, respectively at the 1 hour
treatment period). Since both viabilities were above 15% the outcome of
both tissues wasclearly
negative. Therefore this deviation has no influence on the study
Although the inter-tissue variability
in viability between two tissues and the maximum difference in
percentage between the mean viability of two tissues and one of the two
tissues treated with HEDTA-H3 were above the acceptability criteria (up
to 44 and 22%, respectively at the 1 hour treatment period), all
individual results obtained were clearly negative. Consequently, this
deviation has no impact on the outcome of the study.
Skin corrosion is expressed as the
remaining cell viability after exposure to the test substance. The
relative mean tissue viability obtained after 3-minute and 1-hour
treatments with HEDTA-H3 compared to the negative control tissues was
86% and 59%, respectively. Because the mean relative tissue viability
for HEDTA-H3 was not below 50% after the 3-minute treatment and not
below 15% after the 1-hour treatment HEDTA-H3 is considered to be not
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