Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Assessment of Stability with regards to hydrolysis was considered inappropriate.

Testing was not carried out according to Method C7 of Commission Directive 92/69/EEC and Method 111 of the OECD Guidelines for Testing of Chemicals, 13 April 2004 because, in accordance with column 2, adaptation of Annex VIII (section 9.2.2.1) "the study does not need to be conducted if the substance is highly insoluble in water (< 1 mg/l) or is rapidly biodegradable. The submission substance has a very low water solubility value (0.21mg/l) and is rapidily biodegradable.

It was not possible to determine the partition coefficient of the test material by Method A8 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC) due to poor solubility and complex nature of substance (UVCB).

The partition coefficient was, however, estimated by a WSKOW (v1.41); Estimation Programs Interface Suite™ for Microsoft® Windows, v 4.00. UnitedStates Environmental Protection Agency.

The partition coefficient for several main compoents of the test material was calculated and estimated to be greater than 4.0.

Based on high Log Kocand low water solubility the substance is likely to adhere to organic matter (e.g. sewage sludge). However, due to rapid degradation in sewage treatment plant, adsorption to sewage sludge is expected to be minimal.

Though the estimated Log Pow is relatively high the subsmission substance is considered not to have the potential to bioaccumulate as it is rapidly biodegradable. Based on the above factors the submission substance is not considered to be classified.

Reliability

The above studies have all been ranked reliability 1 (reliability 2 for the QSAR prediction) according to the scoring system of Klimisch et al. This ranking was deemed appropriate because the studies were conducted to GLP and in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of relevant results.