Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 219-371-7 | CAS number: 2425-79-8
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The substance was not acutely toxic to Daphnia magna when tested according to OECD 202. The calculated 24-h EC50 is 75 mg/L (nominal) with 95% CL of 65 - 90 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 75 mg/L
Additional information
Acute toxicity to Daphnia magna was assessed according to OECD 202 in a study not following GLP procedures (Rufli, 1989). Daphnia were exposed under static conditions to the substance at a range of concentrations from 10, 18, 32, 58, or 100 mg/L in freshwater. The test was performed with 5 daphnia per vessel and 20 daphnia per concentration. For each concentration, the percentage of immobilisation at 24-hours was recorded. The test concentrations were not confirmed by analytical monitoring. The following OECD 202 validity criteria were met: immobilisation in the control did not exceed 10% at the end of the test, and concentrations of dissolved oxygen in the control and test vessels remained above 3 mg/L at the end of the test. The 24-h EC50 was calculated as the geometric mean of the EC0 (32 mg/L) and the EC100 (>100 mg/L). Under the conditions of the test, the calculated 24-h EC50 was 75 mg/L, and the graphically determined 24-h EC50 was 76 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
