Registration Dossier
Registration Dossier
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EC number: 415-430-8 | CAS number: 86403-32-9 CYASORB UV-3853 LIGHT STABILIZER; DASTIB 845; SANDUVOR 845
Endpoint summary
Administrative data
Description of key information
Additional information
The main components of CPSS 53 are rapidly converted to 2,2,6,6-tetramethylpiperidin-4-ol (CAS 2403-88-5), palmitic acid and stearic acid. The fatty acids are biodegraded by microorganisms.
The other product of ester hydrolysis, 2,2,6,6-tetramethylpiperidin-4-ol, is
not readily biodegradable, as seen in the biodegradation study (OECD
301C) and in an OECD SIDS dossier for
2,2,6,6-tetramethylpiperidin-4-ol; nor does it hydrolyze at pH 4, 7 and
9 at 50 °C after 5 days. Using EPIWIN to
estimate degradation for this peperidin-4-ol, the BIOWIN2 (value of
0.3910) and BIOWIN6 (value of 0.4812) predictions are below 0.5 whereas
BIOWIN3 predicts a half live between weeks-months (value of 2.6118).
This is evaluated as “not readily biodegradable”.
Due to the fact that only primary degradation of CPSS 53 is detected, a
clear conclusion whether the persistence criterion (P of PBT) is met
could not be drawn from the available data. Although for the main
components of CPSS 53 rapid primary degradation is proven, the
degradation product 2,2,6,6-tetramethylpiperidin-4-ol might fulfill the
P / vP criterion. Therefore for precautionary reasons CPSS 53 is
considered to fulfill the P criterion.
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