Registration Dossier
Registration Dossier
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EC number: 415-430-8 | CAS number: 86403-32-9 CYASORB UV-3853 LIGHT STABILIZER; DASTIB 845; SANDUVOR 845
Dissociation constant
Administrative data
Link to relevant study record(s)
Description of key information
Waiver
Key value for chemical safety assessment
Additional information
Dissociation tests were not conducted due to the low water solubility of the notified chemical. The secondary amine group in the piperidine ring is sterically hindered by the four methyl substituents on the adjacent carbon atoms. Consequently, while aliphatic secondary amine groups typically have pKa values between 9.5 and 10.5, in the present case the amine group lone pair may be significantly shielded by the four bulky methyl groups resulting in a significantly lower value for pKa.
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