Registration Dossier

Environmental fate & pathways

Adsorption / desorption

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Administrative data

Endpoint:
adsorption / desorption
Remarks:
other: QSAR
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
QSAR prediction.

Data source

Reference
Reference Type:
other: QSAR
Title:
KOCWIN v2.00
Author:
EPA’s Office of Pollution Prevention Toxics and Syracuse Research Corporation.
Year:
2000
Bibliographic source:
http://www.epa.gov/opptintr/exposure/pubs/episuite.htm

Materials and methods

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Adsorption coefficientopen allclose all
Type:
log Koc
Value:
-1.304
Remarks on result:
other: Estimated from the Log Kow
Type:
log Koc
Value:
1
Remarks on result:
other: Estimated from the MCI method.

Applicant's summary and conclusion

Conclusions:
Depending on the calculation method used, the log Koc was found to be -1.3040 (based on log Kow) or 1.00 (based on MCI method).
Executive summary:

The log Koc was calculated by EpiSuite's KOCWIN model.

The suitability of the model was assessed and it was concluded that L-histidine is considered to be inside the applicability domain of the EpiSuite KOCWIN model.

Depending on the calculation method used, the log Koc was found to be -1.3040 (based on log Kow) or 1.00 (based on MCI method).