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EC number: 215-710-8
CAS number: 1344-95-2
Daily urinary excretion
of SiO2 in volunteers before and after ingestion of synthetic
Sum SiO2 day 1 – 3 [mg/d] (control)
Sum SiO2 day 4 – 7 [mg/d](test phase)
Sum SiO2day 1 – 3 [mg/d] (control)
During the four days post-treatment, significant changes of the renal SiO2 excretion were not seen.
Daily SiO2 increments in urine after ingestion ranged between individually
7 and 23 mg, but were barely distiguishable
from the baseline level.
The individual baseline values of the pretest phase were very variable and individually different, mean excretion rates ranging from
25 to 87 mg/d. In the post-treatment phase, individual mean excretion rates ranged from 32 to 61 mg/d.
The individual baseline values of the pretest phase were very variable and individually different, mean excretion rates ranging
from 16 to 71 mg/d.
In the post-treatment phase, individual mean excretion rates ranged from 20 to 81 mg/d.
Overall, increases in excretion of SiO2 after oral ingestion were not
The small apparent increases on
the average of less than 0.5 % of the total dose
were in marked contrast to the high dose of 2500 mg SiO2 applied.
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