Registration Dossier
Registration Dossier
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EC number: 215-710-8 | CAS number: 1344-95-2
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Approx. 20 years of experience from exposed workers gave no evidence of skin sensitisation/allergic contact dermatitis in conjuction with exposure to calcium silicate (see also Chapter 7.10.4). This is consistent with approx. 50 years of occupational experience with synthetic amorphous silica, the parent substance (see ECETOC 2006).
Further testing has been waived based on REACH Regulation, Annex XI.
Migrated from Short description of key information:
No experimental data in animals available. There is no evidence of skin sensitisation in exposed workers over decades of practical experience.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
- Migrated from Short description of key information:
No experimental data available. There is no evidence of respiratory sensitisation after approx. 50 years of experience from workers exposed to calcium silicate or silica.
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
